Physiological cost of walking in those with chronic fatigue syndrome

<b>Purpose:</b> To examine the physiological cost of walking in subjects with chronic fatigue syndrome (CFS) and a matched control group, walking at their preferred and at matched walking speeds. <b>Methods:</b> Seventeen people with CFS and 17 matched-controls participated in this observational study of physiological cost during over-ground gait. Each subject walked for 5 min at their preferred walking speed (PWS). Controls then walked for 5 min at the same pace of their matched CFS subject. Gait speed and oxygen uptake, gross and net were measured and oxygen uptake was expressed per unit distance ambulated. CFS subjects completed the CFS-Activities and Participation Questionnaire (CFS-APQ). <b>Results:</b> At PWS the CFS group walked at a slower velocity of 0.84 ± 0.21 m s<sup>-1</sup> compared to controls with a velocity of 1.19 ± 0.13 m s<sup>-1</sup> (p < 0.001). At PWS both gross and net oxygen uptake of CFS subjects was significantly less than controls (p = 0.023 and p = 0.025 respectively). At matched-velocity both gross and net physiological cost of gait was greater for CFS subjects than controls (p = 0.048 and p = 0.001, respectively). <b>Conclusion:</b> The physiological cost of walking was significantly greater for people with CFS compared with healthy subjects. The reasons for these higher energy demands for walking in those with CFS have yet to be fully elucidated

Gait characteristics of subjects with chronic fatigue syndrome and controls at self-selected and matched velocities

Background: Gait abnormalities have been reported in individuals with Chronic Fatigue Syndrome (CFS) however no studies exist to date investigating the kinematics of individuals with CFS in over-ground gait. The aim of this study was to compare the over-ground gait pattern (sagittal kinematics and temporal and spatial) of individuals with CFS and control subjects at their self-selected and at matched velocities. Methods: Twelve individuals with CFS and 12 matched controls participated in the study. Each subject walked along a 7.2 m walkway three times at each of three velocities: self-selected, relatively slow (0.45 ms-1) and a relatively fast (1.34 ms-1). A motion analysis system was used to investigate the sagittal plane joint kinematics and temporal spatial parameters of gait. Results: At self-selected velocity there were significant differences between the two groups for all the temporal and spatial parameters measured, including gait velocity (P = 0.002). For the kinematic variables the significant differences were related to both ankles during swing and the right ankle during stance. At the relatively slower velocity the kinematic differences were replicated. However, the step distances decreased in the CFS population for the temporal and spatial parameters. When the gait pattern of the individuals with CFS at the relatively fast walking velocity (1.30 ± 0.24 ms-1) was compared to the control subjects at their self-selected velocity (1.32 ± 0.15 ms-1) the gait pattern of the two groups was very similar, with the exception of both ankles during swing. Conclusion: The self-selected gait velocity and/or pattern of individuals with CFS may be used to monitor the disease process or evaluate therapeutic intervention. These differences may be a reflection of the relatively low self-selected gait velocity of individuals with CFS rather than a manifestation of the condition itself

An additional study and implementation of tone calibrated technique of modulation

The Tone Calibrated Technique (TCT) was shown to be theoretically free from an error floor, and is only limited, in practice, by implementation constraints. The concept of the TCT transmission scheme along with a baseband implementation of a suitable demodulator is introduced. Two techniques for the generation of the TCT signal are considered: a Manchester source encoding scheme (MTCT) and a subcarrier based technique (STCT). The results are summarized for the TCT link computer simulation. The hardware implementation of the MTCT system is addressed and the digital signal processing design considerations involved in satisfying the modulator/demodulator requirements are outlined. The program findings are discussed and future direction are suggested based on conclusions made regarding the suitability of the TCT system for the transmission channel presently under consideration

Measuring situation awareness in complex systems: Comparison of measures study

Situation Awareness (SA) is a distinct critical commodity for teams working in complex industrial systems and its measurement is a key provision in system, procedural and training design efforts. This article describes a study that was undertaken in order to compare three different SA measures (a freeze probe recall approach, a post trial subjective rating approach and a critical incident interview technique) when used to assess participant SA during a military planning task. The results indicate that only the freeze probe recall method produced a statistically significant correlation with performance on the planning task and also that there was no significant correlation between the three methods, which suggests that they were effectively measuring different things during the trials. In conclusion, the findings, whilst raising doubts over the validity of post trial subjective rating and interview-based approaches, offer validation evidence for the use of freeze probe recall approaches to measure SA. The findings are subsequently discussed with regard to their implications for the future measurement of SA in complex collaborative systems

The Detectability of AGN Cavities in Cooling-Flow Clusters

Chandra X-ray Observatory has revealed X-ray cavities in many nearby cooling flow clusters. The cavities trace feedback from the central active galactic nulceus (AGN) on the intracluster medium (ICM), an important ingredient in stabilizing cooling flows and in the process of galaxy formation and evolution. But, the prevalence and duty cycle of such AGN outbursts is not well understood. To this end, we study how the cooling is balanced by the cavity heating for a complete sample of clusters (the Brightest 55 clusters of galaxies, hereafter B55). In the B55, we found 33 cooling flow clusters, 20 of which have detected X-ray bubbles in their ICM. Among the remaining 13, all except Ophiuchus could have significant cavity power yet remain undetected in existing images. This implies that the duty cycle of AGN outbursts with significant heating potential in cooling flow clusters is at least 60 % and could approach 100 %, but deeper data is required to constrain this further.Comment: 4 pages, 2 figures; to appear in the proceedings of "The Monsters' Fiery Breath", Madison, Wisconsin 1-5 June 2009, Eds. Sebastian Heinz & Eric Wilcots; added annotation to the figur

The powerful outburst in Hercules A

The radio source Hercules A resides at the center of a cooling flow cluster of galaxies at redshift z = 0.154. A Chandra X-ray image reveals a shock front in the intracluster medium (ICM) surrounding the radio source, about 160 kpc from the active galactic nucleus (AGN) that hosts it. The shock has a Mach number of 1.65, making it the strongest of the cluster-scale shocks driven by an AGN outburst found so far. The age of the outburst ~5.9e7 y, its energy about 3e61 erg and its mean power ~1.6e46 erg/s. As for the other large AGN outbursts in cooling flow clusters, this outburst overwhelms radiative losses from the ICM of the Hercules A cluster by a factor of ~100. It adds to the case that AGN outbursts are a significant source of preheating for the ICM. Unless the mechanical efficiency of the AGN in Hercules A exceeds 10%, the central black hole must have grown by more than 1.7e8 Msun to power this one outburst.Comment: 4 pages, 5 figures, accepted by ApJ

Jet Interactions with the Hot Halos of Clusters and Galaxies

X-ray observations of cavities and shock fronts produced by jets streaming through hot halos have significantly advanced our understanding of the energetics and dynamics of extragalactic radio sources. Radio sources at the centers of clusters have dynamical ages between ten and several hundred million years. They liberate between 1E58-1E62 erg per outburst, which is enough energy to regulate cooling of hot halos from galaxies to the richest clusters. Jet power scales approximately with the radio synchrotron luminosity to the one half power. However, the synchrotron efficiency varies widely from nearly unity to one part in 10,000, such that relatively feeble radio source can have quasar-like mechanical power. The synchrotron ages of cluster radio sources are decoupled from their dynamical ages, which tend to be factors of several to orders of magnitude older. Magnetic fields and particles in the lobes tend to be out of equipartition. The lobes may be maintained by heavy particles (e.g., protons), low energy electrons, a hot, diffuse thermal gas, or possibly magnetic (Poynting) stresses. Sensitive X-ray images of shock fronts and cavities can be used to study the dynamics of extragalactic radio sources.Comment: 10 pages, 3 figures, invited review, "Extragalactic Jets: Theory and Observation from Radio to Gamma Ray, held in Girdwood, Alaska, U.S.A. 21-24 May, 2007, minor text changes; one added referenc

Chronicity and Mental Health Service Utilization for Anxiety, Mood, and Substance Use Disorders among Black Men in the United States; Ethnicity and Nativity Differences.

This study investigated ethnic and nativity differences in the chronicity and treatment of psychiatric disorders of African American and Caribbean Black men in the U.S. Data were analyzed from the National Survey of American Life, a population-based study which included 1859 self-identified Black men (1222 African American, 176 Caribbean Black men born within the U.S., and 461 Caribbean Black men born outside the U.S.). Lifetime and twelve-month prevalence of DSM-IV mood, anxiety, and substance use disorders (including Bipolar I and Dysthmia), disorder chronicity, and rate of mental health services use among those meeting criteria for a lifetime psychiatric disorder were examined. Logistic regression models were employed to determine ethnic differences in chronicity, and treatment utilization for disorders. While rates of DSM-IV disorders were generally low in this community sample of Black men, their disorders were chronic and remained untreated. Caribbean Black men born in the U.S. had higher prevalence of Post-Traumatic Stress Disorder, Major Depressive Disorder, and Alcohol Abuse Disorder compared with African American men. Foreign born Caribbean Black men experienced greater chronicity in Social Phobia and Generalized Anxiety Disorder compared to other Black Men. Utilization of mental health service was low for all groups of Black Men, but lowest for the foreign born Caribbean Black men. Results underscore the large unmet needs of both African American and Caribbean Black men in the United States. Results also highlight the role of ethnicity and nativity in mental disorder chronicity and mental health service utilization patterns of Black men

MTDC systems for frequency support base on DC voltage manipulation

This paper presents control strategies for multi-terminal HVDC systems to provide primary frequency support to connected AC networks via coordinated DC voltage manipulation. Inertia response from DC connected large offshore wind farms can also be incorporated without telecommunication based on the detection of DC voltage derivation. Simulation studies ba sed on a 3-terminal HVDC system connecting one large wind farm and two separate AC networks validate the operation of the system during frequency events

The StarScan plate measuring machine: overview and calibrations

The StarScan machine at the U.S. Naval Observatory (USNO) completed measuring photographic astrograph plates to allow determination of proper motions for the USNO CCD Astrograph Catalog (UCAC) program. All applicable 1940 AGK2 plates, about 2200 Hamburg Zone Astrograph plates, 900 Black Birch (USNO Twin Astrograph) plates, and 300 Lick Astrograph plates have been measured. StarScan comprises of a CCD camera, telecentric lens, air-bearing granite table, stepper motor screws, and Heidenhain scales to operate in a step-stare mode. The repeatability of StarScan measures is about 0.2 micrometer. The CCD mapping as well as the global table coordinate system has been calibrated using a special dot calibration plate and the overall accuracy of StarScan x,y data is derived to be 0.5 micrometer. Application to real photographic plate data shows that position information of at least 0.65 micrometer accuracy can be extracted from course grain 103a-type emulsion astrometric plates. Transformations between "direct" and "reverse" measures of fine grain emulsion plate measures are obtained on the 0.3 micrometer level per well exposed stellar image and coordinate, which is at the limit of the StarScan machine.Comment: 24 pages, 8 figures, accepted for PAS